Current Focus

  • DNA damage tolerance in yeasts and higher eukaryotes

  • Uev1 in Signal Transduction, Immunity and Cancer

  • Ubc13-Uev mediated Lys63 ubiquitination

  • Mechanisms of gene regulation in response to DNA damage

  • Signal transduction in response to environmental stresses

Other Projects

  • O6-Methylguanine DNA repair methyltransferase and its functions

  • Roles of mismatch repair in acquired DNA alkylation tolerance

  • Molecular cloning and characterization of additional DNA alkylation repair genes

  • Genetic interactions between base excision repair and other repair pathways

  • Molecular cloning and characterization of the yeast and human NGS1/MRE11

Past Experience & Publications

  • Molecular evolution of the yeast 2µm plasmid

  • Genetic manipulations of the industrial Saccharomyces yeasts

  • The yeast and plant acetolactate synthase gene and herbicide resistance

  • Other Publications